- May 30, 2013 at 12:52 am #105354
kjones02ParticipantTopics: 79Replies: 315
After hearing about methylglycine, and reading about tmg, also mentioned on the protocol; I came upon reading about Dimethylglycine. Anyone know about it? Seems good for the brain and immune response.
Dimethylglycine (DMG) is a derivative of the amino acid glycine. It is found naturally in plant and animal cells and in certain foods such as beans, cereal grains, and liver. DMG is produced in cells during the metabolism of choline (1) and is considered an antioxidant and enhancer of oxygenation at the cellular level (2). It has been found that choline and DMG are present at higher levels in fetal than in maternal plasma, suggesting that choline provides glycine via DMG for glutathione synthesis in fetal development (3). Plasma DMG levels have also been found to be lower in children with cystic fibrosis than in healthy children (4). DMG has purported use in enhancement of the immune system, stimulation of neurological functions, management of autism and epilepsy (1) (5) (6). Some studies have shown that DMG may help enhance both humoral and cell-mediated immune responses in humans and animals (2) (7), enhance oxygen utilization during hypoxia, reduce lactic acid build-up in the blood during stressful events, and the number of seizures (1). However, conflicting data suggest that DMG has no effect on either specific or nonspecific immunity (8). DMG was also found to have no effect on oxygen consumption (VO2) in children with SLSJ-COX deficiency (9). The use of DMG to treat seizures or autism also stays controversial as clinical trials have yielded mixed results (1) (10) (11). DMG is non-toxic (7) and no significant adverse effects have been reported. DMG should not be confused with trimethylglycine (TMG), also know as betaine, that is involved in the methylation of homocysteine to form methionine.
Attention deficit-hyperactivity disorder
Chronic fatigue syndrome
Read this review about a mom helping her child:
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