I didn’t say that enemas cause skin and eye irritation. I said that irritation of your intestinal tract is a well-known cause of skin and eye irritation.
You can do enemas as much as you like. As long as those enema’s don’t irritate your intestines, you are unlikely to suffer from skin or eye problems.
But if, for whatever reason, the enemas do irritate your intestines, then it it not unlikely that you’ll develop skin and/or eye irritation.