Colonization of Beneficial Bacteria Obtained from Oral Probiotics

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    The research:

    A study was conducted on human subjects to test the colonization ability of oral probiotics containing specific strains of lactobacillus given as a probiotic supplement to a group of 12 volunteers; the volunteers were given a total of two doses a day for a total of 17 days at which point the lactobacillus probiotic was stopped. The volunteers then went through an 18-day washout period in an attempt to clear the intestines of beneficial bacteria. During this time, feces of the volunteers were tested for strains of bacteria. The samples were taken at days 0 and 18 during the oral dose period as well as during and following the washout period. The highest number of volunteers who continued to host the specific lactobacillus bacteria strains throughout the washout period as well as afterwards was 10 out of 12 of the subjects; the lowest number hosting the species of lactobacillus was 7 out of 12 samples.

    I don’t know how the point was completely proven by the study because I don’t have access to the full details of the study but only the published report; however, according to the report, the experiment revealed that specific beneficial bacteria of the lactobacillus species obtained by human beings via the oral administration or probiotics were capable of colonization in the human intestines.

    This was reported in the Applied and Environmental Microbiology Journal in April 2010 as well as the Therapeutic Advances in Gastroenterology Journal in May 2011.


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