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When I initially was just ridding myself of the run-of-the-mill yeast infection, I used 3 200 mg each tablets spaced out over 7 days like the doc prescribed. I tried another round just like that when lip rash and cracks in the corners came up, didn’t do a thing. Perhaps if I did it for a long period of time, it would work, but I don’t like the idea of taking diflucan for that long. Also, I would have to talk a doctor into it, which seems like it would be impossible since they don’t believe in systemic yeast. 🙁