The berberine in the goldenseal is still going to go into the bloodstream since anything rubbed on the body is absorbed into the skin and eventually the bloodstream. Plus, you’re going to lick your lips occasionally. If you want to try it, just be alert for any worsening of the Candida symptoms, and I wouldn’t want to use it for a prolonged period of time.
Of course, the problem isn’t really located on the lips – if this were true, one would be able to rub a strong antifungal on the lips and they would stop hurting after a while because the Candida would be dead, but this isn’t the case. I had the same problem and the pain didn’t go away until the infestation started diminishing to a considerable degree. I probably tried a dozen different products, all to no avail until I realized the problem was inside me, not on my lips. Regular Vaseline seemed to help more than anything else.
If you see no improvements after 24 hours, I would stop using the goldenseal ointment.