There is an strong link between CRC and autoimmune diseases. Candida Albicans can suppress cell-mediated immunity and down regulate the suppressor cells. The suppressor cells are those that regulate an immune response against our own tissues and organs.
Wouldn’t this tie into adrenal fatigue/hypothyroid since the endocrine systems play an important role in regulating the immune system through hormones?
From my understanding it’s almost impossible to NOT have a compromised immune system by the time CRC happens, since a faltering immune system is what allows it to get out of control. To me this suggests adrenal/thyroids are a component to solving this puzzle – tail chasing: what came first scenarios. I’m leaning towards the endocrine systems being the first to crash in the chain reaction but, that just this week. ha!
As always, Jorge thank you for sharing your generous and informative insight.
Natacha – you are correct in how leaky gut is part of this syndrome from my understanding but, I wouldn’t say foreign particles since they are mostly large molecule food particles the body doesn’t recognize as food and mounts an immune response to what it thinks are invaders. Think leaky gut causes much of the histamine reactions typical of CRC sufferers.
Yes, this is what happens:
Chronic antigenemia, occurring naturally or
induced experimentally, may result in immunologic
unresponsiveness to specific
antigens, including those of infectious origin.
Antigens that evoke a normal immune response
initially may induce immunologic tolerance
when antigenic exposure becomes of the
quantity and duration critical to its
establishment. With its immunologic defenses
neutralized, the host becomes incapable of
eliminating from its tissues the source of
tolerizing antigen, insuring perpetuation of the
compromised immune response and persistence
in the tissues of the infectious agent.
Total loss of immune capability is suggested
by the terms “immunologic paralysis” and
“immunologic unresponsiveness”; “immunologic
tolerance” may perhaps better describe a
continuing but ineffectual immune response that
“tolerates” rather than rejects the organism. The
“ebb and flow” in the opposing forces of foreign
invasion and immune rejection is reflected
clinically in the remissions and exacerbations
characteristic of many chronic illnesses. The
incompleteness of “paralysis” is suggested by
fluctuations both in clinical manifestations and
in such simple tests of normal immune activity
as the white blood cell count, skin test response,
body temperature, and antibody titer, as well as
by the inconstancy of indicators of abnormal
immunologic activity, e.g., immune complex
deposition, RA factor, LE cell, ANA. The
pattern of the clinical response may undergo
constant change as the immune system reacts
both normally and abnormally to the qualitative
and quantitative variations in antigenic
Persistence of Candida albicans in the tissues
for prolonged periods typifies these principles.
Chronic symptoms representing systemic
responses to soluble yeast products accompany
manifestations referable to the infected sites.
Both fluctuate according to the effectiveness of a
weakened immune response that is often
influenced by factors directly favorable to yeast