The future Universal Super-Probiotic

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This topic contains 5 replies, has 3 voices, and was last updated by  Floggi 6 years, 6 months ago.

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  • #89223

    dvjorge
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    #89232

    Floggi
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    Looks very promising.

    The principle of this idea is similar to the less hygienic circumstances under which humanity evolved. Back then, it was quite normal to transfer fecal bacteria between members of the same tribe.

    Though this therapy is promising, I understand that it’s not yet ready for mainstream application, because the risks aren’t well known yet. Therefore, it will take a while to assess the risks. Only after knowing the risks can we decide when this therapy is a good solution, and when it would do more harm than good.
     

    #89247

    Bucephalus
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    It’s actually being performed in the US and Australia by some gastros. Maybe some other places too. It’s only new, but this procedure will be more and more used in the future. It’s already been done for at least two years, I don’t know how long you have to wait before it’s considered safe.

    #89250

    Floggi
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    It’s not a matter of “just someone” trying this for some time.

    It’s a matter of a supervised trial, double-blind, randomized and controlled if possible, with a sufficient number of patients.
     

    #89260

    Bucephalus
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    Please explain:
    Double blind:
    Randomised:
    Controlled:

    Thanks.

    #89264

    Floggi
    Member
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    Oops… I really thought that this terminology would be well-known in a community that is so closely related to medical research…

    I seem to have been wrong in my assumption…

    The background of this terminology is that there are a lot of pitfalls if you want to find out if something works, and you “just try”. These pitfalls work both ways: there is a high likelihood that you will think that something does not work even if it does, and there is an even higher likelihood that you will think that something does work even if it does not.

    Decennia of trying, evaluating, and learning have resulted in what is now considered a “golden standard” of medical research.

    If you want to have meaningful results, any test setup must be:

    Randomised
    You do research on a lot of test persons – the more the better. Half of those gets the treatment you want to test, the other half either gets a placebo treatment or a treatment with a known cure. Randomised means that patients are assigned to one of these two groups in a totally random way.

    Double blind
    Neither the doctor nor the patient may have any knowledge about the treatment. That is, neither of the two may have any way of knowing whether that particular patient receives the treatment that is tested, or the other treatment.

    Controlled
    Everything that is done is recorded, from the random assigning of each patient to one of the two groups, to the actions that are taken, to the results, and any possible side effects. In addition, if at all possible, anything else that the patient does in parallel to the investigation is recorded.

    This is the only way to do research. If you forget one of these three parts of the golden standard, your results will be unreliable.
     

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