MTHFR Results Not Too Good

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This topic contains 74 replies, has 9 voices, and was last updated by  impossible 5 years, 2 months ago.

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  • #114030

    blueocean
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    Topics: 1
    Replies: 17

    As for family history, my Mother is 59 and she was recently diagnosed with Lupus. Lots of inflammation, stiffness, rashes, etc is what led to the diagnosis. Before that she had some bouts of depression and some eating disorders (anorexia) but no other serious issues. My maternal grandmother died at age 79 from a rare muscle disease called IBM – eventually fell and broke her hip and died of kidney failure a few months later. She was diagnosed at age 76 and before that she had no health problems and she was a 2 pack a day smoker. Maternal Grandfather died at age 81 from a heart attack, no health problems up to the day he dropped dead while working. He never once went to the hospital in his life & autopsy said he had heart disease but he never knew it.

    On my fathers side, he died young, age 49 from a drug overdose. He suffered from depression and severe social anxiety. Paternal grandmother died at age 82, she had altheimers and I’m not exactly sure what the cause of death was. Paternal Grandfather I don’t know much about other than he died at age 78 and I was told from natural causes but that’s not a good explanation.

    My sister had rheumatoid arthritis as a child, had preeclampysia with both of her pregnancies and both kids were born very premature, and now she recently got diagnosed with polycystic kidney disease. I’m pushing her to get her DNA tested but she hasn’t yet.

    We haven’t had any cancer in my immediate family.

    #114034

    runmillerun
    Member
    Topics: 4
    Replies: 18

    can someone tell me what those tests are MTFHR??? and how much they cost. I had mercury fillings to as a child. I have 6 removed 2 years ago. What testing would be good to get. What is thie 23andme test? I would love to know about these two tests if someone can be so kind to explain them. Thank you.

    #114036

    blueocean
    Member
    Topics: 1
    Replies: 17

    runmillerun;52555 wrote: can someone tell me what those tests are MTFHR??? and how much they cost. I had mercury fillings to as a child. I have 6 removed 2 years ago. What testing would be good to get. What is thie 23andme test? I would love to know about these two tests if someone can be so kind to explain them. Thank you.

    I would recommend this site for you to start, there is a video there that explains it:

    http://mthfr.net

    #114038

    impossible
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    Topics: 16
    Replies: 606

    Be careful with your mother, im not even sure I would use methyl support with something like lupus, theres the possibility or evenn probability that it could make the inflammation much worse. It would be best to consult a specialist, the best you can find, in a case like that. Are you aware of the viral connection they are beginning to make with lupus? Have you heard of LDN?

    #114039

    blueocean
    Member
    Topics: 1
    Replies: 17

    impossible;52559 wrote: Be careful with your mother, im not even sure I would use methyl support with something like lupus, theres the possibility or evenn probability that it could make the inflammation much worse. It would be best to consult a specialist, the best you can find, in a case like that. Are you aware of the viral connection they are beginning to make with lupus? Have you heard of LDN?

    Thanks Impossible. I have not heard of the viral connection with Lupus. My mother has been fighting it for 2 years now and it isn’t pretty at all. She’s in fairly bad shape.

    Do you think the Lupus is at all related to this gene mutation?

    #114040

    impossible
    Member
    Topics: 16
    Replies: 606

    psalm34810;52542 wrote: How might I receive some help with my 23andme results? I have a chart like the one printed above, perused Dr. Yasko’s book and frankly am a bit baffled by the MTHFR stuff. My pattern of 2 years of daily seizure attack episodes and pain/sickness is finally beginning to change with aggressive treatment for stage 3 Candida (ie. severely restricted diet, supps & meds). The the treatment focus began in 2011 with clinical Lyme then biotoxin illness (cyanobacteria & mold). Methylation seems to be the way to go to get well!

    Wow you’ve come a long way. You should do a write up on your experience with lyme and biotoxin illness, im trying to raise awareness on this site, I’ve seen some people on here that looked fairly obvious to me, but sometimes people are slow to accept new ideas. Do you know what your haplotype is?

    I wouldnt get your hopes up or anything like that as far as methylation being the answer. It can be an answer for those it is a problem for, but its some cure for everything by any means. I would be glad to take a look at your panel though.

    #114041

    impossible
    Member
    Topics: 16
    Replies: 606

    blueocean;52560 wrote:

    Thanks Impossible. I have not heard of the viral connection with Lupus. My mother has been fighting it for 2 years now and it isn’t pretty at all. She’s in fairly bad shape.

    Do you think the Lupus is at all related to this gene mutation?

    Methylation problems are being discovered to be a large part of the development of lupus, in the majority its begining to seem like. Look into low dose naltreone. That stuff is a life saver for many with lupus, even gets some off the meds. Make sure you find a practitioner that is well versed in using it in cases like your mothers. Methylation induced inflammation will override ldn’s effectiveness for future referance.

    #114044

    impossible
    Member
    Topics: 16
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    I was going to post a link, but there is so many, just search ebv and lupus.

    #114045

    raster
    Participant
    Topics: 104
    Replies: 6838

    psalm34810;52542 wrote: My pattern of 2 years of daily seizure attack episodes and pain/sickness is finally beginning to change with aggressive treatment for stage 3 Candida (ie. severely restricted diet, supps & meds).

    I personally think you are wasting your time looking into methylation cycles to solve your seizure problems. What you need is to get the spinal fluid draining again because it is getting blocked up. When it blocks up, your body has a seizure to get the fluid to release because there is too much pressure in the head.

    How do I know? I’ve cured my seizures…

    What did I take to cure my seizures? I started to take essential fatty acids (E3AFA’s); your brain is made up largely of fat and so these fatty acids help heal your brain. I also take something that gets the spinal fluid flowing again…its called super neurogen DHA by genestra.

    “The brain, an organ highly concentrated in lipids, undergoes rapid growth and development beginning in the third trimester and continuing throughout childhood.The health and integrity of the nervous system, including the brain, relies on properly formed neural tissue. Studies indicate the DHA plays a crucial role in the repair and regeneration of neural tissue which affects retinal, visual, learning and memory function. Research shows that DHA decreases inflammatory mediators such as arachidonic acid, making it effective in inflammatory conditions such as arthritis, ear infections, and skin disorders. DHA has also been shown to have an effect on the cardiovascular system by reducing serum triglyceride levels and increasing serum high-density lipoprotein cholesterol levels. Super Neurogen DHA assists in the development of the neural tube and retina, and in the prevention of spina bifida; and is indicated for all neurovegetative conditions, including Parkinson’s and Alzheimer’s diseases, and schizophrenia. It is also recommended for attention deficit hyperactivity disorder, cardiovascular disease, hypertension, arthritis, eczema, psoriasis, and depression.”

    The candida toxins are likely partially eroding your brain, as well as other personal habits such as drug use, alcohol use (prior), caffeine, sugar, grains such as corn and wheat, etc.

    I also take a few homeopathics before I go to sleep and this prevent them also.

    I’ve been seizure free since my birthday this year…I only get them when I drink alcohol now, so I won’t drink it anymore.

    Don’t take these supplements unless you consult a doctor, etc.

    -raster

    #114046

    raster
    Participant
    Topics: 104
    Replies: 6838

    Question: Does consuming fatty acids and addressing the neurological system via supplements…is it considered to be part of the methylation cycle?

    -raster

    #114049

    impossible
    Member
    Topics: 16
    Replies: 606

    What you are failing to understand in the case of that person is the effect of biotoxins, from both mold and lyme/coinfections, and the resulting neuro inflammation. For some people, its actually an effect of the innate immune system. Seizures are a common symptom of that.

    No, that is not a part of the methylation cycle. But, many inflammatory and neuro diseases at their heart are caused by poor methyl cycle function, look at autism or Alzheimers as an example.

    #114105

    blueocean
    Member
    Topics: 1
    Replies: 17

    I’m going to use this thread as a log and document the supplements I’m taking as well as any improvements i’m feeling.

    To go after the ammonia/sulfer issues due to CBS mutation first I’ll be taking the following:

    1. Molybdenum 75mcg twice per day
    2. Yucca Root 200mg twice per day
    3. Boron 3mg per day
    4. Vitamin E Succinate 400 IU per day
    5. Low Sulfate/Sulfite Diet and Lower Animal Protein
    6. (Heartfixer site also recommends Hydroxy B12 at 2000mcg / Day but I’m not sure how this will interfere with the mb12 I need for the MTHFR mutation)

    Next I will tackle the MTHFR issues:

    1. MethylFolate (Quatrefolic) starting at 200mcg per day up to 800mcg per day
    2. Methyl B12 Sub-lingual starting at 100mcg up to 200mcg per day
    3. Betaine 200mg

    Impossible – One question: How long should I wait to begin the Methyl treatments for the MTHFR issues? Should I run the CBS treatment plan for awhile or should I start them both together?

    #114120

    impossible
    Member
    Topics: 16
    Replies: 606

    Start cbs treatment for a week or 2 at first, if its not bothering you much. For people that have it bad, a month or even more was necessary. You might do better cutting those starting doseages in half, or even quarter. Use enzymatic therapy b12, by far the best, and cheapest.

    #114179

    impossible
    Member
    Topics: 16
    Replies: 606

    You might need to supplement potassium too. Muscle spasms and anxiety are the 2 most common symptoms of deficiency, which often occurs when adding needed methyl support.

    #114351

    blueocean
    Member
    Topics: 1
    Replies: 17

    This is my 3rd day on the CBS protocol and I feel pretty good. My mood is enhanced and I’m sleeping better and had some nice, vivid dreams which I never have or at least I never can remember. Improved energy as well, slightly.

    I did cut the doses in half on everything except the molybdenum and the GABA and added a charcoal supplement taken away from all the other supps.

    Impossible – I’m also taking a calcium, magnesium, potassium supplement at night before bedtime so that should cover the potassium. It’s the powdered form, Natural Calm supplement, really helps with my sleep. Do you see any issues with this? Here are the ratios per serving:

    Calcium Gluconate 230mg, Magnesium Citrate 350mg, Potassium Citrate 115mg.

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