- July 23, 2018 at 12:10 pm #176406
I’ll be undergoing the dvjorge protocol (somewhat). I’ve done a fair amount of research into his posts, dating back to 2012. Thought I’d share the research I’ve done so far – hopefully it helps someone. Out of everything I’ve found online re candida, I feel his knowledge is in another league entirely.
Here we go:
/different species of candida/
“The thing is Boric Acid is effective against Candida Tropicalis and Candida Glabrata. Fluconazole is weak against Glabrata. You probably had an infection with a non-albican species. I have written posts about it before.”
“Candida Glabrata is in the second order regarding to the infectious rate. Candida Glabrata isn’t a polymorphic yeast but can penetrates and invade the cells. C. Glabrata is intrinsically resistant to Diflucan. If this is your case, Fluconazole won’t touch it.
Intrinsically resistance can not be solved by combining antifungals. It must be another type of antifungal.”
“Most of the time, an intestinal reservoir of yeast colonies manipulates the immune system favoring mucosal yeast overgrowth. In other words, if your intestines are infected, your vagina is. There is a correlation between the intestinal growth with other body part infections.”
“During an active infection, yeasts invade underlying tissues and penetrate inside epithelial cells, where they stop growing, but continue to release yeast digestive enzymes and toxic metabolic products that cause chronic tissue irritation. I coined the phrase latent intracellular yeast infection for this condition.”
“CRC ( Candida Related Complex ) is a syndrome caused by an intestinal yeast overgrowth, sometimes genital too, and its metabolites affecting remote organs and functions.”
“Cured people have followed long term systemic and non systemic antifungal therapies, immune stimulation with candida antigen, and chelation protocols in the case that heavy metal toxicity be identified.”
“[..]losing an effective immune response to control yeast overgrowth and germination. The “normal” yeast mono-cells living in the vagina and colon turn germ tubes and filamentous. This form is able to penetrates the epithelial cells. Since our cell protection (Th1) is partially blocked, candida albicans penetrates the cells. One time inside the cells, it adopts a non-growing form but still able to produce enzymes and metabolites. It is known as an intracellular candidiasis. This is what is causing your vulvar pain and burning feeling.
The thing is a little bit complex since the cell-mediated dominance is controlled by yeast colonies in the intestines. In a few words, to eliminate the intracellular vaginal infection you need to correct the immune suppression power yeast colonies are causing inside the gut.”
“Regaining cell-mediated immunity is the only path to cure chronic mucosal fungal infections.”
/role of immune system/
“Candida sufferers don’t catch common flu because they are Th2 over-active. This means your immune response is toward to an antibody production. This overactivity in the Th2 arm is protecting you against any extracellular intruder. However, their intracellular defenses are very low allowing candida to growth. A balanced immune system is necessary to protect us against all the health offenders. You need a Th1/Th2 balanced immune system. If any of these arms work chronically polarized, we are going to have health problems.”
“That is the reason because you read it can not be cured. Yes, it can not be cured until the immune deficiency be corrected. You can reduce candida colonies taking antifungals and following an strict diet but one time you release it, the fungus begin to growth again. It is a PROPER immune response what holds the fungus growing on our mucosal areas.
The focus must be immune restoration even when this includes a drastic candida elimination from the infected areas.”
“The typical case of someone affected by this syndrome is a depressed cell-mediated immunity and an overactive humoral immunity. This over-activity in the Th2 immune response is what cause the hypersensitive state candida sufferers have. The humoral immunity reacts to many things “normal” people don’t react Th2 is too sensitive and reinforced when Th1 is depressed.
The immune system must be balanced to function correctly.”
“Candida release MANNAN inside the intestines. This metabolite drives the immune system toward to a Th2 response suppressing Th1. In a few words, the intestinal overgrowth is responsible for the immune suppression that don’t allow you to cure your vaginal yeast infection.”
“Distinct suppression of cell-mediated immune response (CMI) was shown in all patients comparing to the control.
[..]You girls having Chronic and recurrent vaginal candidiasis should consider taking Cimetidine and Zinc for 3 months.”
/immune stimulation shots – allergist/
“Regarding to Dr. Crandall[..] is also one who has insisted to me that immune shots are really important because they reverse the immune tolerance to an active immune response to candida albicans.
“I went to his office with a copy of an article written by Dr. Truss where he mentions the concentration.”
So, I advice you to get the immune stimulation shot even if you are symptom free. If you have access to an Allergist that will be able to cooperate and give you the shots, don’t hesitate.”
“The shots are more productive when the candida load is reduced to a minimum since candida manages the immune system.”
“Hypo-sensitization shots reactivate the immune system to attack candida again. Persistent mucosal candidiasis is an immune fail no matter if the antibiotics or other cause aggravate it.
There is a point where the immune system ( cell-mediated immunity) don’t respond to the yeast anymore. This is the candida opportunity to invade tissue.”
/cimetidine and immune function/
“[Re immune system support] Bovine Transfer Factor, Earth Dragon Peptides, Zinc, Lactoferrin, Vitamin D, Omega 3, Vitamin C ( high doses).
Don’t take Cimetidine. Leave it in case you need a powerful Cell-mediated immune booster. Learn about it as immune booster, side effects, etc.”
“Cimetidine 1200 mg a day plus 50 mg of Zinc are boosting and modulating my immune system toward to cell-mediated immunity, a necessary thing to overcome the mucosal candidiasis.”
“Cimetidine has the highest record as an immune modulator than any other over the counter medical drug available. It has been used against terminal cancers, AIDS, etc.”
/intracellular yeast penile/
“A systemic antifungal drug is necessary when yeast go intracellular and deep inside the tissues. Topical treatments DON’T work when people experience an intracellular penile yeast infection.
It must be an effective systemic antifungal drug to cure it. When yeast go intracellular (very common after treated with topical creams) there isn’t swap or superficial test that can detect it. The best thing you can do is to ask for a treatment trial. You can explain to his Dr yeast are deep in the tissues and can not be detected with a swap collection.
The only solution for it is a systemic drug. He may respond to it perfectly and eliminate it. He needs a proper dosage according to his weight and age. Lowering the dosage doesn’t help. Proper and for long enough effective treatment.”
/azole drugs and ibuprofen/
“Buy Advil liquid gel capsules or any other Ibuprofen brand but liquid gel capsules. Open the capsules and mix 3 or 4 drops with 1/2 teaspoon of Clotrimazole cream. ”
“Probably 400 or 600 mg a day is enough. (ibuprofen, with azole drug)”
“The headquarter is in the Cecum. This is the most difficult part to treat of the complete infestation. Metabolites produced by candida colonies in the Cecum influence the immune system causing cell-mediated suppression. Candida albicans cells living in other mucous membranes begin to produce symptoms since there isn’t immune control. I believe I still have candida colonies in the Cecum. Very hard to treat orally and very difficult rectally. High enemas and retention antifungal enemas that reaches the Cecum are probably the only hope. Resolving the intestinal overgrowth fixes the rest of the problems most of the time.”
/lactulose as a prebiotic/
“Lactulose is probably the best Prebiotic known so far to increase lactic acid bacteria in the colon, specially Bifidos count.”
“Lactulose increases colonic anaerobic bacteria faster than anything, specially indigenous Bifidos species. This increment will reduce candida spores considerable since lactic acid bacteria produce anti-yeast by-products such as acetic, lactic, and butyric acids. They lower the intestinal Ph antagonizing the yeast growth. It is also effective against pathogenic bacteria and streps.”
“I have told people should target candida orally and rectally. Both way. The medical evidence stays most of the fungal colonies live in the cecum.”
“All you need to be sure is to avoid chlorinate water. Tap water is chlorinate. Bleach kills bacteria !!!
Any supermarket sales distilled or purified water. The water won’t ruin your protocol as long it doesn’t have bleach.”
“I’ve perfected the technique somewhat recently.”
“I clean the colon with water first, and as a last round I do one with 500 000 units [Nystatin] dissolved in 6 ounces of water that I hold inside of me until the next day.”
/retention enema technique/
“1. Empty the colon via clear water enema (usually takes between 1-4 rounds)
2. A normal round is usually 4-6 cups of water and a little sea salt (32 – 48 oz)
3. Afterwards, Mix 4-6 oz of water with Nystatin powder (can be 1 or more tbps of powder) and retain this mixture in the colon for an extended period of time (I could easily retain 4 oz until the next day)”
“Nystatin retention enemas are targeting the colon lumen, an area very difficult to reach where the most concentration of candida colonies live.”
/curcumin for nystatin enemas/
“I suggest you mixing the Nystatin solution with Curcumin (Turmeric) You need to clean the colon with water enemas before to insert the antifungal solution. Around 4 or 6 ounces are enough. Try to hold it until the next day. I don’t know how concentrated the Nystatin solution is but think around of 500 000 units each dosage. You may add a capsule of Curcumin to the Nystatin solution, at least one time a week.”
“I have used Curcumin mixed with Nystatin myself without any problem.
Curcumin is a very effective anti-inflammatory substance. It will help the colon inflammation and stress during the enema cycles.
Curcumin is also antifungal but the most important is it has shown synergistic effects when mixed with the azoles and polyenes. The mix become Fungicidal causing fungal cells apoptosis.
So, adding a capsule of Curcumin to the Nystatin solution will increase the antifungal activity and will help with the stress of the continued enemas.”
/re low carb diet/
“You need to follow a LOW carbohydrate diet. I mean low not a 0 carbohydrate diet. Your sugar level must be in range. Total sugar deprivation in the intestinal lumen encourage yeast to migrate and to digest tissues. Candida Albicans becomes more pathogenic when it transforms in a filamentous form.”
“Interfase Plus contain two enzymes that affects candida cell wall. Chitinase and Glucanase. These are the two more important enzymes. Forget about Cellulase and Hemicellulase.”
“Echinocandins are a new class of antifungal drugs that inhibit the synthesis of glucan in the cell wall, via noncompetitive inhibition of the enzyme 1,3-β glucan synthase and are thus called “penicillin of antifungals” (a property shared with papulacandins) as penicillin has a similar mechanism against bacteria but not fungi.”
“I read some time ago that there is one oral version on developing. They aren’t absorbed well by the intestinal lining and cause stomach side effects. They probably found how to correct it.”
“S. Boulardii has to be used without anything antifungal.”
“It is an excellent product. I have studied it deeply,reading all the studies I have found about it. S. Boulardii is great, specially after some intensive antifungal protocol.”
“Don’t take any antifungal when using S. Boulardii. You need at least 25 billions a day. ”
“Clear water enemas plus a retention enema with S. Boulardii. I mean, do 2 or 3 rounds of clear water enemas enough to evacuate the colon. (as clean as possible) then, prepare an enema fleet bottle with 4 ounces of water and an S. Boulardii capsule.
Insert this solution in the colon and try to hold it as much as possible, until the next day, if possible. You should try it for at least 2 months. Do the enemas 3 times a week and respect the diet.”
“I have seen people improving dramatically with [just] S. Boulardii, enemas, and diet.”
“My refer to Florastor doesn’t mean that I have proof that another brand isn’t going to work. I am telling Florastor because the success stories I am aware of were using Florastor.
Jarrow Formulas S. Boulardii has Maltodextrin. Maltodextrin is a tremendous growing factor for yeast. ”
“S. Boulardii segregates Capryc Acid that impedes candida adhesion to the epithelial cells. It also modulate the inflammatory response inside the gut facilitating the growth of lactic acid bacteria.”
“S. Boulardii is the flag ship treatment against candida for autistic children ( go to Autism forums) It is sold over the counter. ”
“10 billions is a low dosage. Rise it to 25 or 30 billions a day. I take 36 billions a day in 4 doses ( 9 billions each ) The retention enemas I have used two open capsules in around 4 or 5 ounces of water. This is 18 billions.”
“My liver enzymes never went high but I don’t advice you to follow this treatment alone. You need a Dr monitoring you. Liver enzymes should be checked every 3 weeks. You need to watch symptoms of liver toxicity. Dark urine, nausea, yellowish skin and white of the eyes, etc. If you see some, stop immediately.”
“Yes, you have to check your liver enzymes every 21 days, but it doesn’t mean they will be altered. I suggest you to take some natural liver support supplement, Lactoferrin 1 g a day, and Alpha Lipoic Acid 400 mg a day ( If you have dental amalgams, don’t take ALA ) These will protect the liver and lactoferrin has synergistic antifungal effects when mixed with Diflucan.”
“To support the liver you should take Sylimarin high doses ( more than 800 mg ), Vitamin E 800 mg a day. Lactoferrin is also a great anti-oxidant. Also, I suggest ALA if you don’t have amalgam fillings. ALA 600 mg a day. ”
“I am almost sure nothing is going to happen to your liver since liver enzyme alteration is rare with these drugs. I have known people in the forums who has taken them for more than a year without any problem. I, myself, have taken Fluconazole for 3 or 4 months without any change in my liver function. You have to take the systemic drug every day.”
“Effective reversion of fluconazole resistance by ibuprofen in an animal model.”
“The standard dose is 200 mg a day. However, Diflucan has a very low impact on the yeast colonies living in the gut lumen. It won’t touch it. So, if you overgrowth is intestinal, you need something non-absorbed that target the fungus living in the lumen.
Since these fungal colonies living in the lumen generates enough metabolites to manipulate your immune system, Diflucan won’t be able to eradicate yeast focus around the body since the immune system is required for it.
People with CRC need Diflucan plus an non-systemic drug (Nystatin, Natamycin, or Oral Amp B. – These are the non-absorbed Rx antifungals I know) long term. Let say 3 or 4 months and to respect an anticandida diet.”
“I have taken Diflucan for months without any problem. Not only Diflucan but Ketoconazole medium/high doses for 3 months without any liver alteration. 500 mg of Ketoconazole diary.”
“Ketoconazole is effective on some strains that are resistant to Fluconazole.
I have tolerated it very well. No huge side effects but I check my liver every 21 days when I use it. I took 400 mg and even 600 mg some days without any problem at all. It was Ketoconazole that eliminated my residual intracellular penile infection.”
“The dosage must be high. I would take 400 mg of Ibuprofen tablets together with the azole during the first 15 days, at least. You may need 800 or 1200 mg of Cimetidine a day too. Cimetidine will boost cell-mediated immunity. ( 400 mg /3 times a day )”
“Diflucan 100 mg is a low dosage. 200 mg a day is the normal doses.”
“Take Nystatin orally, no less than 3 millions of units a day plus curcumin capsules. Keep the diet and do the enemas plus retention enemas.”
“I won’t use ANY natural antifungal in the colon, less GSE.
All naturals are antibacterial. The secret is to use a PURE antifungal with no effect on bacteria and no able to cross the colon lining. It is Nystatin.”
“Yes, pure alcohol doesn’t feed candida, but I don’t advice it. However, a drink probably does little harm.”
/tests for Candida/
“My favorite tests to confirm mucosal candidiasis (intestinal yeast overgrowth)[..]
Delayed Sensitivity Test on Skin
It is a simple test where an Allergist applies candida albicans antigen on the skin with a light scratch. Then, they cover the area. You have to come back to the Allergist’s office to read the test after 48 hours. If the test shows positive (an increase in redness and inflammation) you have a proper cell-mediated response to candida albicans. This is what is expected after the antigenic provocation. If the skin isn’t irritated, inflamed, and red, your immune system is tolerating the presence of candida on the skin. In other words, it doesn’t combat it.
This test is extremely valuable to know there is a hidden immune suppressor or acquired cell-mediated immunity deficiency that allows candida to colonize our mucosal areas. Maybe an immune defect, mercury, deficient methylation, or any other thing.
Candida Immunecomplexes in Blood (Genova Lab)
When candida growth occurs in the intestines, it releases fragments of its cell wall during the growing phase, which are soluble and able to reach the bloodstream where they are seen as antigens by our humoral immune response. Immediately, an active antibody binds with every single candida antigen circulating in our blood.
The test analyzes the blood under a microscopic, and an skilled technician detects these immunecomplexes (bond between antibody/antigen) present in the blood. There isn’t way you have a fungal intestinal overgrowth without having yeast fragments of complement circulating in the blood.”
/chelation of metals/
“Yes, correct chelation protocols have been a huge miracle for many people. You are correct, Andy Cutler system is the best you can find. It isn’t only the most effective but the safest of all of them.”
“I have also re-started a chelation protocol after 3 months resting it. I was chelating with ALA 50 mg tablets for a year and 3 months when I stopped it.”
“I am not sure what is the root of my candidiasis but chelating with effective chelators, driving the pathogens out of the tissues, should revert any acquired tolerance or acquired immune suppression.”
“Mercury toxicity is a hidden cause affecting methylation and pushing the immune system toward to a humoral response.”
“ALA (Alpha Lipoic Acid) is the best oral chelator agent known. It is ALA that will bind with Mercury and transport it to your evacuation channels.”
You need a chelator that have at least two thiol molecules to ensure an strong bond. ALA, DMSA, and DMPS bind strong enough to ensure the mercury won’t be released anywhere in the body.
Get the book ” The Amalgam Illness” by Dr. Andy Cuttler.”
“Candida hyphal growth is dependent on mg sources. [..] Yes, I have mentioned it before warning people about magnesium intake.”
“[..]a central regulatory role for Mg in C. albicans morphogenesis.”
/re rotating antifungals/
“Combining antifungals are the best way to treat candida. As you said, randomly rotation is risky since you may chose one that doesn’t have any activity against the strain is affecting you. During the time you take one with low or no activity, candida colonies will re-growth and may develop resistance since the survivor cells are what are genetically stronger.
If some antifungal is working, keep it. Then add another one. You may rotate the second one if you wish but never what you know is giving you die-off reaction. If the second one increases your symptoms, then, don’t rotate that one either.”
“You can read here the case in the vagina. Same thing happens in the intestines.”
“It was found that Candida species can penetrate, invade, develop and proliferate within the deep layers of intact cells of the cervix and vaginal mucosal epithelium.”
https://www.ncbi.nlm.nih.gov/m/pubmed/6175129/July 26, 2018 at 12:10 am #176461
CandidaThovexParticipantTopics: 0Replies: 3
This is amazing work! Thank you for compiling all of this information!
Do you have a copy of his protocol all together in one place anywhere?
Also, do you know what probiotics he recommends? I’m working through research and compiling all of the vitamins and minerals and antifungals that I will need right now, just not sure which probiotics or prebiotics I should be using…
Thanks again!July 26, 2018 at 12:15 pm #176467
I don’t think he places an emphasis on probiotics. As far as I can tell his protocol focuses on reducing fungal load in the colon, as well as re strengthening the immune system.
From what I remember, dvjorge has taken a strong stance against pharmaceutical probiotics, effectively calling them useless.
I would go with probiotic foods like kimchi, kefir (home made), natto, etc.
And you’re welcome! Hopefully it helps somewhat. His protocol is the sum of his post contributions to this forum and others. This is as much “all in one place” as I think it things will get. Took me a few weeks to put it all together – I was doing it for myself but then figured I would share.July 26, 2018 at 5:58 pm #176469
Wiley200ParticipantTopics: 2Replies: 355
Thanks!July 27, 2018 at 10:17 pm #176478
CandidaThovexParticipantTopics: 0Replies: 3
Clandestine: you’re doing enemas? Have you done them from the start? Are they effective? I plan to only do them if I can’t completely remove the candida via antifungals & dietary changes.July 28, 2018 at 12:00 am #176479
Clandestine: you’re doing enemas? Have you done them from the start? Are they effective? I plan to only do them if I can’t completely remove the candida via antifungals & dietary changes.
I’m about to start doing them. I was able to acquire Nystatin powder without any added sugar.
Jorge feels that you cannot eliminate Candida with dietary changes alone. This is something that I tend to agree with and have found to be true over the last 8 years in suffering with this condition.
I’m hoping enemas will make a difference this time around – time will tell.
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