- September 14, 2013 at 2:04 pm #110312
jameskepParticipantTopics: 25Replies: 220
3. Inhibition of N-myristoyltransferase The enzyme myristoyl-CoA; protein N-myristoyltransferase (NMT) recognises chain length rather than hydrophobicity of fatty acids and attaches tetradecanoic (myristic) acid (14:0) to the amino-terminal glycine of eukaryotic proteins, leading to an irreversible protein modification 51,52]. N-myristoyltransferase is essential for growth and survival of several fungi and yeasts  with any of the fungal species synthesizing a variety of N-myristoyl proteins using NMT as a catalyst. Several myristic acid analogues have been shown to compete with 14:0 for binding to NMT, resulting in disturbance of protein function . Table 4 lists myristic acid analogues proposed to inhibit fungal NMT
Go to table 4 from the above link…
This product seems to help..still experimenting with. Myristic acid seems to be less irritating than capric acid, or undecenoic acid.
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