dvjorge;54047 wrote: Alletess Candida panel
Organic Acid Test (Organix Comprehensive Profile – Genova Diagnostics)
GI Effects Comprehensive Profile – Genova
CPL lab blood draw to include: MTHFR (L), metobolic panel, lipid panel, ANA, CBC, CRP – high sensitivity, Ferritin, Homocysteine, Iron, T3 Free, TSH, Vit D.
These are good tests but not my preferred to detect a chronic candida problem.
Candida antibody panel (IGE, IGM, IGA, IGG) is a test detecting a humoral immune response which isn’t too much implicated during a mucosal yeast overgrowth. Most probably it will be negative or slightly positive if an allergic reaction to candida is present.
Organic Acid Test in urine can show metabolic yeast by-products in urine when an overgrowth is present in the intestines. There are some of these metabolites only produced by yeast. If there isn’t a significant intestinal overgrowth, this test won’t show anything. Anyway,it is a valuable test. We will see the results.
GI Effects (cdsa) is an excellent test but not a definitive tool to rule out an intestinal yeast overgrowth. Candida is an intracellular pathogen able to penetrate our cells and tissues.
Stool tests, even the most advanced, aren’t effective detecting an intestinal yeast overgrowth.
My favorite tests to confirm mucosal candidiasis are Delayed Sensitivity Test on skin and Candida Immunecomplexes in blood. These two are what says the last word.
If someone suspects having an intestinal yeast overgrowth, the best test is Candida Immunecomplexes in blood (currently only done by Genova Lab) Why ?? Because when candida growth in the intestines, it releases fragments of its cell wall during the growing phase, those fragment are soluble and able to reach the bloodstream where they are seen as antigens by our humoral immune response. Immediately, an active antibody binds with every single candida antigen circulating in our blood. The test analyzes the blood under a microscopic, and an skilled technician detects these immunecomplexes (bond between antibody/antigen) present in the blood. There isn’t way you have a fungal intestinal overgrowth without having yeast fragments of complement circulating in the blood.
The other test, one very important, is the Delayed Sensitivity Test on skin. It is a simple test where an Allergist applies candida albicans antigen on the skin with a light scratch. Then, they cover the area. You have to come back to the Allergist’s office to read the test after 48 hours. If the test shows positive ( an increase in redness and inflammation ) you have a proper cell-mediated response to candida albicans. This is what is expected after the antigenic provocation. If the skin isn’t irritated, inflamed, and red, your immune system is tolerating the presence of candida on the skin. In other words, it doesn’t combat it.
This test is extremely valuable to know there is a hidden immune suppressor or acquired cell-mediated immunity deficiency that allows candida to colonize our mucosal areas. Maybe an immune defect, mercury, deficient methylation, or any other thing.
This isn’t complicated but people need education. The web is plagued with myths and mistakes.
How do I find someone who administers the CANDIN test or similar? Now that I’ve gained a better understanding of what you’re talking about it makes more sense. I am curious though, since my son tests positive for Auto-Immune Disorder and has previously reported a depressed SIgA, would that indicate at TH1 issue already or would the CANDIN test tell us something different?
You also recommended a test by Genova Labs which I know my functional MD can order. Is this just as good as the CANDIN test? It would be easier for me to get the Genova Test since he’s familiar. For whatever they’re worth, here’s the results of the Alletess Candida test. If these results change your opinion on which test I should do, please let me know.
Candida Albicans: IgG 42, IgA 18, IgM 75
Immune Complex: 60
Also, On the Organic Acid Test there wasn’t any abnormal yeast but this was reported under “Bacterial – General”: Hippurate – HIGH; Phenylacetate – HIGH; and Indican – HIGH. Not sure if those mean anything to you.
Thanks so much!