i take anti depressants and have since shortly before starting my diet. i had read about how it helped with chornic fatigue..along with some other vitamins like Vit C, Glutamine, and a couple others. i have always taken them off and on all my life but i felt this time i wanted to try them for chronic fatigue. i was having severe body aches every single night, tired very badly every day. it was horrible.so the first day i started taking them, the aches went away. it was AWESOME. so i was taking 2 a day and have now cut back to one a day. i will stop taking them soon but wanted them to keep working a little longer. i cant tell if i am having any issues taking them otherwise. but i definitely dont regret taking them cause they DID help me stop aching. and to describe the aching i had. it was flu like body aches.