Stop the SAMe at this point if you’re taking the b-right. If you get to the point where you feel like the pendulum swung too far the other way add some back in, but at a smaller doseage. I doubt you will need to.
Add in some calcium rich vege’s, cant beat the real thing, supplemental forms are poorly absorbed and utilized. Dark leafy greens are an excellent source.
When did it start? Is it constant? Do you have any periods of total relief? How do you do with a flight of stairs?