Reply To: MTHFR Results Not Too Good

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blueocean;54017 wrote: Just an update from me…. I don’t feel too much different. I’ve been sleeping much better but I think it’s magnesium and GABA helping with that issue. I have noticed that I have been a bit irritable the past few days, no o symptoms just a bit of irritability. Impossible, could that be a sign of overmethylation?

It can be. Anxiety and a general feeling of over-stimulation are some of the typical symptoms. For some people it eventually tapers off, others it gradually gets worse. Most people have success with cutting back and titrating up slowly when they run into this. But, everyone is different.