Reply To: Losing faith in humanity and homeopathy…

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dvjorge
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raster;38624 wrote:

Neither the saliva nor the urine pH correlates to blood pH, so reading the pH of the urine doesn’t tell you anything about
the general pH of the body, only a waste-filled by-product of the body, urine

I agree with it. Moreover, taking antiacid substances has been documented as a cause of intestinal candidiasis.
In my position, I don’t take them.

Jorge.

I guess we’ll see how it goes then. I am doing the alkalization therapy very slowly and hope to continue going to the mineral hot springs as well. I noticed my pH becomes completely pH neutral (7.0) after going to the hot springs for a few days so I know I am getting close. Please don’t tell me the hot springs are bad for me and my pH levels. The homeopathic I take is the main thing that influences my long-term pH levels to ensure that things don’t get out of whack. Once I am neutral for a period of time I am going to start chelation.

-raster

Raster,
I wish you success. You know now that you have to observe it closely. I have read trusted data that rising the intestinal Ph promotes candida pathogenesis.

This abstract mentions the influence of Ph on morphogenesis and pathogenesis. Note that candida albicans cells can influence its external Ph.

ABSTRACT

pH homeostasis is critical for all organisms; in the fungal pathogen Candida albicans, pH adaptation is critical for virulence in distinct host niches. We demonstrate that beyond adaptation, C. albicans actively neutralizes the environment from either acidic or alkaline pHs. Under acidic conditions, this species can raise the pH from 4 to >7 in less than 12 h, resulting in autoinduction of the yeast-hyphal transition, a critical virulence trait. Extracellular alkalinization has been reported to occur in several fungal species, but under the specific conditions that we describe, the phenomenon is more rapid than previously observed. Alkalinization is linked to carbon deprivation, as it occurs in glucose-poor media and requires exogenous amino acids. These conditions are similar to those predicted to exist inside phagocytic cells, and we find a strong correlation between the use of amino acids as a cellular carbon source and the degree of alkalinization. Genetic and genomic approaches indicate an emphasis on amino acid uptake and catabolism in alkalinizing cells. Mutations in four genes, STP2, a transcription factor regulating amino acid permeases, ACH1 (acetyl-coenzyme A [acetyl-CoA] hydrolase), DUR1,2 (urea amidolyase), and ATO5, a putative ammonia transporter, abolish or delay neutralization. The pH changes are the result of the extrusion of ammonia, as observed in other fungi. We propose that nutrient-deprived C. albicans cells catabolize amino acids as a carbon source, excreting the amino nitrogen as ammonia to raise environmental pH and stimulate morphogenesis, thus directly contributing to pathogenesis.

IMPORTANCE Candida albicans is the most important fungal pathogen of humans, causing disease at multiple body sites. The ability to switch between multiple morphologies, including a rounded yeast cell and an elongated hyphal cell, is a key virulence trait in this species, as this reversible switch is thought to promote dissemination and tissue invasion in the host. We report here that C. albicans can actively alter the pH of its environment and induce its switch to the hyphal form. The change in pH is caused by the release of ammonia from the cells produced during the breakdown of amino acids. This phenomenon is unprecedented in a human pathogen and may substantially impact host physiology by linking morphogenesis, pH adaptation, carbon metabolism, and interactions with host cells, all of which are critical for the ability of C. albicans to cause disease.

We propose that nutrient-deprived C. albicans cells catabolize amino acids as a carbon source, excreting the amino nitrogen as ammonia to raise environmental pH and stimulate morphogenesis, thus directly contributing to pathogenesis.

This is an important part to consider since there are studies postulating that nutrient deprived candida cells find the way to germinate and migrate. It means pathogenesis and tissue invasion. Think about what may promotes a very restrictive diet !!

Jorge.