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Usually probiotic supplementation is done when the “fungal” candida is at the bare minimum. Fungal candida is stronger than yeast probiotics so you want to convert candida to its less pathogenic yeast form before you supplement with probiotics/S.boulardi. If someone has too much fungal candida probiotics might just cause uncomfortable symptoms with no results–meaning the fungal candida will just wipe out the probiotic before it even has a chance to colonize and the only end result you get is a bad die-off symptoms.