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Thanks for the correction and the additions, Jorge.
I seem to have mixed up ‘antigen’ and ‘antibody’, and I missed the immune complexes.
One question relating to these immune complexes. As I understand them, they are the result of the binding of the antibodies that are produced by our immune system to the antigens that are produced by the invader (in this case: candida). However, this is all on the molecular level, so it’s invisible under a microscope.
I’m specifically asking about this point because in Europe (don’t know about the USA), LBA is marketed as being able to see candida cells (!) in the blood through a microscope. This, of course, is nonsense, so it’s no surprise that LBA (at least in its European form) was quite easily proved a scam.
How about the USA form of LBA? What exactly does it see through the microscope?
And, back to the candida: in my understanding, immune cells diffuse through the body (they can leave the bloodstream), encounter candida, and then produce antibodies. These antibodies can then be detected in the blood (that’s what I was talking about in my first response), even though the candida itself is not present in the blood. Is this part of my understanding still correct, or am I missing something here too?
Immune complexes are seen using electron microscope. LBA claims of candida cells are false, here, in Europe, or anywhere. It is possible to see live candida cells present in the blood but I bet a million when this happens the person has only a few hours to get emergency treatment to safe his/her life.
It is possible they see fragments of the yeast cell wall or immune complexes and wrongly they claim it is candida live cells.
Yes, antibodies can be detected in blood, even when the infection doesn’t exist anymore. However, in the case of this syndrome, the protective immune response is cell-mediated (th1)
This syndrome is caused by a mucosal fungal infection. Antibodies aren’t the main immune response in this case. If candida reaches serum (blood), the antibodies are the main defense. This is another matter.
A candida antibody blood panel isn’t effective because the infection is mucosal, and the humoral response don’t play a big role. Moreover, many healthy people have an slightly elevated candida antibody levels in blood because the battle between the immune system and candida begins since we are born. Candida is an intruder, a foreign organism that colonizes our tissues. It doesn’t belong to us, so the immune system has a 24 hours battle against it for life. The opposite is possible too. Some people have a severe mucosal yeast overgrowth and don’t show a positive antibody result because they are immune compromised.
The acquired immune tolerance to candida is probably the main cause of this syndrome. If the antigen has lived with you for years, the immune system stops attacking it and begins to accept it as part of you. This happens when the antigen has been enough time with enough presence living in our body. It is known as an immune paralyzes.
Anyway, the way to go is Candida Immune Complexes in blood.